Btrworlds can provide most competitive Mevalonate Pathway Analysis Service,
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Mevalonate pathway, also known as HMG-CoA reductase pathway or the isoprenoid pathway, is an important metabolic pathway essential in eukaryotes, archaea, and some bacteria. The mevalonate pathway is widely studied. This pathway is widely known being involved in cardiovascular diseases. Recently, a large number of experimental and clinical studies show that inhibition of non-sterol isoprenoids has important therapeutical implications. By synthesizing sterol isoprenoids, such as cholesterol, and non-sterol isoprenoids, this pathway plays an essential role in various cellular processes. Starting with acetyl-CoA, the mevalonate pathway ends with two five-carbon building blocks names as isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) used for making isoprenoids like cholesterol, coenzyme Q10, and all steroid hormones. This pathway, specifically HMG-CoA reductase in the mevalonate pathway, is a well-known target of a class of cholesterol lowering drugs-statins. Statins inhibits the activity of HMG-CoA reductase, and thereby inhibits the generation of cholesterol- one kind of isoprenoids.
Creative Proteomics is the proteomics division of Creative Dynamics Inc, an integrated CRO company that provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies.
Creative Proteomics specializes in a full range of services to support various proteome-related researches from identification of single proteins to large-scale proteomic studies. We have one of the most advanced proteomics platforms in the world and our staff scientists are experienced proteomics professionals. Our proteome analysis platform provides protein separation, characterization, identification and quantification services, featured with high throughput and super-sensitivity. In addition, analyses of protein post-translational modifications such as phosphorylation and glycosylation are available.